Anti-South American/Mojave rattlesnake crotoxin Recombinant Antibody (Al0G) (ZA049013)

Name: Anti-South American/Mojave rattlesnake crotoxin Recombinant Antibody (Al0G)
Brand: abinScience
SKU: ZA049013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

ZA049013

Species reactivity

Crotalus durissus terrificus, Crotalus scutulatus scutulatus

Applications

ELISA, FCM, IF, SPR, WB

Host species

Mouse

Isotype

IgG2a

Clone ID

Al0G

Clonality

Monoclonal

Target

Phospholipase A2 crotoxin basic subunit CBc, CB1, CTX subunit CBc, svPLA2, 3.1.1.4, Phosphatidylcholine 2-acylhydrolase, Basic phospholipase A2 Mtx-b, svPLA2, 3.1.1.4, Mojave toxin basic chain, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 CB1, Crotalus durissus terrificus (South American rattlesnake), Crotalus scutulatus scutulatus (Mojave rattlesnake)

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P62022, P62023

RRID

Anti-South American/Mojave rattlesnake crotoxin Antibody (Al0G) (abinScience Cat# ZA049013, RRID:AB_3729020)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Phospholipase A2 crotoxin basic subunit CBc is a ~15 kDa protein. Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission. It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CBa2, CBb, CBc, or CBd), with a small acidic, non-enzymatic and non-toxic subunit (CA1, CA2, CA3 or CA4). The complex acts by binding to a specific 48-kDa protein (R48) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert myotoxicity, nephrotoxicity, and cardiovascular toxicity.

1. Sampaio, SC. et al. (2010) Toxicon : official journal of the International Society on Toxinology 55, 1045-60. PMID: 20109480

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-South American/Mojave rattlesnake crotoxin Antibody (Al0G)

References

Datasheet

Anti-South American/Mojave rattlesnake crotoxin Recombinant Antibody (Al0G).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-South American/Mojave rattlesnake crotoxin Recombinant Antibody (Al0G) (ZA049013)

Overview

Images

References

Datasheet

SDS

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