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Anti-SOX4 Polyclonal Antibody (HB342014)

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Overview
Catalog No.HB342014
Description
Anti-SOX4 Polyclonal Antibody (HB342014) is a rabbit polyclonal antibody detecting Transcription factor SOX-4; SOX4 in ELISA, IHC, WB. Suitable for Human, Mouse, and Frog.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant human SOX4 (Met1-Tyr128).
Target Transcription factor SOX-4; SOX4
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q06945, Q06831, Q91731, P40650, Q62249, O15370, Q04890
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Transcription factor SOX-4 (SOX4) is a ~47 kDa protein. Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif. Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression. Involved in skeletal myoblast differentiation by promoting gene expression of CALD1.

1. Zawerton, A. et al. (2019) American journal of human genetics 104, 246-259. PMID: 30661772
2. Jang, SM. et al. (2015) Cell death & disease 6, e1857. PMID: 26291311
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-SOX4 Polyclonal Antibody

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