Anti-SOX9 Polyclonal Antibody (HW480014)

Name: Anti-SOX9 Polyclonal Antibody
Brand: abinScience
SKU: HW480014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HW480014

Description

Anti-SOX9 Polyclonal Antibody (HW480014) is a rabbit polyclonal antibody detecting SOX9 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Callithrix jacchus, and Dog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SOX9 (Met1-Lys151).

Target

Transcription factor SOX-9, SOX9

Purification

Purified by antigen affinity column.

Accession

P48436

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Transcription factor SOX-9 (SOX9) is a ~56 kDa protein. Transcription factor that plays a key role in chondrocytes differentiation and skeletal development. Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes COL2A1, COL4A2, COL9A1, COL11A2 and ACAN, SOX5 and SOX6. Also binds to some promoter regions. Plays a central role in successive steps of chondrocyte differentiation. Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes.

1. Matsushita, M. et al. (2013) American journal of medical genetics. Part A 161A, 2528-34. PMID: 24038782

2. Südbeck, P. et al. (1996) Nature genetics 13, 230-2. PMID: 8640233

Note

For research use only.

Images

References

Datasheet

Anti-SOX9 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-SOX9 Polyclonal Antibody (HW480014)

Overview

Images

References

Datasheet

SDS

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