Anti-SREBF1/SREBP1 Polyclonal Antibody (HW748014)

Name: Anti-SREBF1/SREBP1 Polyclonal Antibody
Brand: abinScience
SKU: HW748014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HW748014

Description

Anti-SREBF1/SREBP1 Polyclonal Antibody (HW748014) is a rabbit polyclonal antibody detecting SREBF1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SREBF1/SREBP1 (Glu30-Leu490).

Target

Sterol regulatory element-binding protein 1, SREBF1, BHLHD1, Transcription factor SREBF1, Sterol regulatory element-binding transcription factor 1, Class D basic helix-loop-helix protein 1, bHLHd1, SREBP-1, SREBP1

Purification

Purified by antigen affinity column.

Accession

P36956

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Sterol regulatory element-binding protein 1 (SREBF1/SREBP1) is a ~121 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis.

1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-SREBF1/SREBP1 polyclonal antibody at 1ug/mL on recombinant SREBF1/SREBP1 (Catalog No. HW748012).

References

Datasheet

Anti-SREBF1/SREBP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-SREBF1/SREBP1 Polyclonal Antibody (HW748014)

Overview

Images

References

Datasheet

SDS

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