

| Catalog No. | VK099044 | ||||
|---|---|---|---|---|---|
| Description |
Anti-SV40 VP2 Polyclonal Antibody (VK099044) is a rabbit polyclonal antibody detecting Minor structural protein VP2 in ELISA, IHC, WB. Suitable for Simian virus 40.
Highlights
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| Species reactivity | Simian virus 40 (SV40) | ||||
| Applications | ELISA, IHC, WB | ||||
| Host species | Rabbit | ||||
| Isotype | IgG | ||||
| Clonality | Polyclonal | ||||
| Immunogen | E. coli - derived recombinant SV40 VP2 (Met1-Arg289). | ||||
| Target | Minor capsid protein VP2, Minor structural protein VP2 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Accession | P03093 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Minor capsid protein VP2 is a ~38 kDa protein. Structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane. Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm. Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or VP3 nuclear localization signal (shared C-terminus). Plays a role in virion assembly within the nucleus in particular through a DNA-binding domain located in the C-terminal region. | ||||
| Note | For research use only |
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