

| Catalog No. | HB636014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-SYN1 Polyclonal Antibody (HB636014) is a rabbit polyclonal antibody detecting SYN1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Bovine.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human SYN1 (Gly160-Ile291). | ||||||||
| Target | Synapsin-1, Brain protein 4.1, SYN1, Synapsin I | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P17600 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Synapsin-1 (SYN1) is a ~74 kDa protein. Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal. Also involved in the regulation of axon outgrowth and synaptogenesis. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level. 1. Fassio, A. et al. (2011) Human molecular genetics 20, 2297-307. PMID: 21441247 2. Lignani, G. et al. (2013) Human molecular genetics 22, 2186-99. PMID: 23406870 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-SYN1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse cerebellum lysate
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