

| Catalog No. | HT178014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human TGFB1I1 (Phe252-Arg390). | ||||||||
| Target | Androgen receptor-associated protein of 55 kDa, Hydrogen peroxide-inducible clone 5 protein, Androgen receptor coactivator 55 kDa protein, ARA55, Hic-5, Transforming growth factor beta-1-induced transcript 1 protein, TGFB1I1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O43294 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1) is a ~49 kDa protein. Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. | ||||||||
| Note | For research use only. |
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