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Anti-TRIP4 Polyclonal Antibody (HB439014)

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Overview
Catalog No.HB439014
Description
Anti-TRIP4 Polyclonal Antibody (HB439014) is a rabbit polyclonal antibody detecting Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; TRIP4; RQT4 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant human TRIP4 (Asp424-Val581).
Target Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; TRIP4; RQT4
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q15650, Q9QXN3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Activating signal cointegrator 1 (TRIP4) is a ~66 kDa protein. Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation. Also involved in androgen receptor transactivation. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1.

1. Kim, HJ. et al. (1999) Molecular and cellular biology 19, 6323-32. PMID: 10454579
2. Yoo, HM. et al. (2014) Molecular cell 56, 261-274. PMID: 25219498
3. Jung, DJ. et al. (2002) Molecular and cellular biology 22, 5203-11. PMID: 12077347
4. Knierim, E. et al. (2016) American journal of human genetics 98, 473-489. PMID: 26924529
5. Hashimoto, S. et al. (2020) Scientific reports 10, 3422. PMID: 32099016
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-TRIP4 Polyclonal Antibody

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