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Anti-UACA Polyclonal Antibody (HV660014)

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Overview
Catalog No.HV660014
Description
Anti-UACA Polyclonal Antibody (HV660014) is a rabbit polyclonal antibody detecting UACA in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human UACA (Ala29-Glu209).
Target UACA, KIAA1561, Uveal autoantigen with coiled-coil domains and ankyrin repeats
Purification Purified by antigen affinity column.
Accession Q9BZF9
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) is a ~162 kDa protein. Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.

Note For research use only.
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Formula
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Anti-UACA Polyclonal Antibody

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