Anti-UBXN2B Polyclonal Antibody (HB411014)

Name: Anti-UBXN2B Polyclonal Antibody
Brand: abinScience
SKU: HB411014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB411014

Description

Anti-UBXN2B Polyclonal Antibody (HB411014) is a rabbit polyclonal antibody detecting UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant human UBXN2B (Leu244-Lys331).

Target

UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q14CS0, P0C627, Q0KL01

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

UBX domain-containing protein 2B (UBXN2B) is a ~37 kDa protein. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase.

1. Uchiyama, K. et al. (2006) Developmental cell 11, 803-16. PMID: 17141156

2. Kress, E. et al. (2013) The Journal of cell biology 201, 559-75. PMID: 23649807

Note

For research use only

Images

Western blot

Lane 1: A549 cell lysate

References

Datasheet

Anti-UBXN2B Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-UBXN2B Polyclonal Antibody (HB411014)

Overview

Images

References

Datasheet

SDS