Anti-UMOD Polyclonal Antibody (HY032014)

Name: Anti-UMOD Polyclonal Antibody
Brand: abinScience
SKU: HY032014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HY032014

Description

Anti-UMOD Polyclonal Antibody (HY032014) is a rabbit polyclonal antibody detecting UMOD in ELISA, IHC, WB. Suitable for Human, Dog, Bovine, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human UMOD (Glu334-Ser589).

Target

Tamm-Horsfall urinary glycoprotein, THP, Uromodulin, UMOD

Purification

Purified by antigen affinity column.

Accession

P07911

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Uromodulin (UMOD) is a ~69 kDa protein. Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia.

1. Hession, C. et al. (1987) Science (New York, N.Y.) 237, 1479-84. PMID: 3498215

2. Schmid, M. et al. (2010) Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 26, 311-8. PMID: 20798515

Note

For research use only.

Images

References

Datasheet

Anti-UMOD Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-UMOD Polyclonal Antibody (HY032014)

Overview

Images

References

Datasheet

SDS

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