Anti-UPB1 Polyclonal Antibody (HV482014)

Name: Anti-UPB1 Polyclonal Antibody
Brand: abinScience
SKU: HV482014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV482014

Description

Anti-UPB1 Polyclonal Antibody (HV482014) is a rabbit polyclonal antibody detecting UPB1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human UPB1 (Trp121-Glu384).

Target

UPB1, N-carbamoyl-beta-alanine amidohydrolase, Beta-ureidopropionase, Beta-alanine synthase, BUP1, BUP-1

Purification

Purified by antigen affinity column.

Accession

Q9UBR1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Beta-ureidopropionase (UPB1) is a ~43 kDa protein. Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable).

1. van Kuilenburg, AB. et al. (2012) Biochimica et biophysica acta 1822, 1096-108. PMID: 22525402

2. Nakajima, Y. et al. (2014) Journal of inherited metabolic disease 37, 801-12. PMID: 24526388

3. Van Kuilenburg, AB. et al. (1999) Analytical biochemistry 272, 250-3. PMID: 10415095

4. Vreken, P. et al. (1999) Biochimica et biophysica acta 1447, 251-7. PMID: 10542323

5. Sakamoto, T. et al. (2001) Journal of nutritional science and vitaminology 47, 132-8. PMID: 11508704

6. Maurer, D. et al. (2018) The Biochemical journal 475, 2395-2416. PMID: 29976570

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-UPB1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse liver lysate
Lane 2: Rat kidney lysate
Lane 3: Rat liver lysate

References

Datasheet

Anti-UPB1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-UPB1 Polyclonal Antibody (HV482014)

Overview

Images

References

Datasheet

SDS

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