Anti-VP1 Polyclonal Antibody (VK079034) is a rabbit polyclonal antibody detecting Capsid protein VP1 in ELISA, IHC, WB.
Highlights
●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
Species reactivity
Hepatitis A virus (HAV)
Applications
ELISA, IHC, WB
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Immunogen
E. coli - derived recombinant Genome polyprotein (Val492-Ser765).
Target
Genome polyprotein, Capsid protein VP0, VP4-VP2, Capsid protein VP4, P1A, Virion protein 4, Capsid protein VP2, P1B, Virion protein 2, Capsid protein VP3, P1C, Virion protein 3, Protein VP1-2A, VPX, Capsid protein VP1, P1D, Virion protein 1, Assembly signal 2A, pX, Protein 2BC, Protein 2B, P2B, Protein 2C, P2C, EC:3.6.1.15, Protein 3ABCD, P3, Protein 3ABC, Protein 3AB, Protein 3A, P3A, Viral protein genome-linked, VPg, Protein 3B, P3B, Protein 3CD, Protease 3C, P3C, EC:3.4.22.28, Picornain 3C, RNA-directed RNA polymerase 3D-POL, P3D-POL, EC:2.7.7.48
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application
Dilution
ELISA
1:5000-1:20000
IHC
1:50-1:500
WB
1:500-1:2000
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background
Genome polyprotein (VP1) is a ~251 kDa protein. Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell.
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