Anti-VPS26A Polyclonal Antibody (HB599014)

Name: Anti-VPS26A Polyclonal Antibody
Brand: abinScience
SKU: HB599014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB599014

Description

Anti-VPS26A Polyclonal Antibody (HB599014) is a rabbit polyclonal antibody detecting Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Frog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant human VPS26A (Met1-Gln305).

Target

Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O75436, P40336, Q6AY86, Q0VD53, Q6DFU4, Q6IRD0, Q6TNP8

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Vacuolar protein sorting-associated protein 26A (VPS26A) is a ~38 kDa protein. Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.

1. Seaman, MN. (2004) The Journal of cell biology 165, 111-22. PMID: 15078902

2. Arighi, CN. et al. (2004) The Journal of cell biology 165, 123-33. PMID: 15078903

3. Vergés, M. et al. (2004) Nature cell biology 6, 763-9. PMID: 15247922

4. Harbour, ME. et al. (2012) The Biochemical journal 442, 209-20. PMID: 22070227

5. Harbour, ME. et al. (2010) Journal of cell science 123, 3703-17. PMID: 20923837

6. Fjorback, AW. et al. (2012) The Journal of neuroscience : the official journal of the Society for Neuroscience 32, 1467-80. PMID: 22279231

7. Gullapalli, A. et al. (2006) Molecular biology of the cell 17, 1228-38. PMID: 16407403

8. Temkin, P. et al. (2011) Nature cell biology 13, 715-21. PMID: 21602791

Note

For research use only

Images

References

Datasheet

Anti-VPS26A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-VPS26A Polyclonal Antibody (HB599014)

Overview

Images

References

Datasheet

SDS