

| Catalog No. | VK422153 |
|---|---|
| Species reactivity | Vesicular stomatitis Indiana virus (VSIV) |
| Applications | ELISA, Neutralization, WB |
| Host species | Mouse |
| Isotype | IgG2a, kappa |
| Clone ID | 8G5F11 |
| Clonality | Monoclonal |
| Target | G, Glycoprotein |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P03522 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Glycoprotein (Glycoprotein G) is a ~57 kDa protein. Attaches the virus to host LDL receptors, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane. 1. Cureton, DK. et al. (2010) PLoS pathogens 6, e1001127. PMID: 20941355 2. Finkelshtein, D. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 7306-11. PMID: 23589850 3. Libersou, S. et al. (2010) The Journal of cell biology 191, 199-210. PMID: 20921141 4. Albertini, AA. et al. (2012) PLoS pathogens 8, e1002556. PMID: 22383886 |
| Note | For research use only |

SDS-PAGE for Anti-VSV G/Glycoprotein G Recombinant Antibody (8G5F11)
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