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Denosumab ELISA Kit (DT439018)

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Overview
Catalog No.DT439018
Description
Denosumab ELISA Kit (DT439018) — Quantitative sandwich ELISA for Denosumab. Sample: Plasma, Serum. Range: 78.125 - 5, 000 ng/mL.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • Ready-to-Use — Complete kit with pre-coated plates included.
Sample typePlasma, Serum
Range78.125 - 5, 000 ng/mL
Accession O14788
Applications ELISA
Detection method Colorimetric
Assay type Quantitative
Recovery 80-120%
Shipping 2-8 ℃
Stability and Storage The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications

Denosumab

Alternate NamesAMG162, HL2001, 615258-40-7
Background

Tumor necrosis factor ligand superfamily member 11 (Denosumab) is a ~35 kDa protein. Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

1. Luan, X. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 245-52. PMID: 22664871
Note For Research Use Only.
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References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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