HEK293T Human NECTIN4/PVRL4 Stable Cell Line (HV985818)

Overview

Catalog No.	HV985818
Description	HEK293T Human NECTIN4/PVRL4 Stable Cell Line (HV985818) is a stable cell line expressing NECTIN4/PVRL4. Engineered for consistent, high-level target expression in research applications. Highlights ●Stable Expression — Engineered for consistent, high-level target expression.
Accession	Q96NY8
Applications	FCM
Species	Human
Host species	HEK293T
Target	NECTIN4/PVRL4
Properties	Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
Stability and Storage	Frozen in liquid nitrogen.
Specifications	1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
Background	Nectin-4 (NECTIN4/PVRL4) is a ~55 kDa protein. Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. NECTIN4 is the therapeutic target of enfortumab vedotin (Padcev).

Images

Flow cytometry

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human Nectin-4 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet