Human IgM Recombinant Antibody (HA529013)

Name: Human IgM Recombinant Antibody
Brand: abinScience
SKU: HA529013
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HA529013
Host species	Human
Isotype	IgM
Clonality	Monoclonal
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P0DOX6
RRID	Human IgM Antibody (abinScience Cat# HA529013, RRID:AB_3730102)
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IgM, Immunoglobulin mu
Background	Immunoglobulin mu heavy chain is a ~63 kDa protein. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170 4. Geisberger, R. et al. (2006) Immunology 118, 429-37. PMID: 16895553
Note	For research use only.

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Human IgM Recombinant Antibody.pdf

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Human IgM Recombinant Antibody (HA529013)

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