InVivoMAb Anti-DENV-2 Pre-membrane protein/prM Antibody (prM12) (VK494010)

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK494010

Description

InVivoMAb Anit-DENV2 Protein prM/prM Antibody (prM12) [prM12] (VK494010) is a human monoclonal antibody detecting Protein prM in ELISA, Neutralization.

Species reactivity

Dengue virus type 2 (strain Thailand/16681/1984) (DENV-2)

Applications

ELISA, Neutralization

Host species

Human

Isotype

IgG1, kappa

Clone ID

prM12

Clonality

Monoclonal

Target

Protein prM, prM

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P29990

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Genome polyprotein (Protein prM/prM) is a ~379 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.

1. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008

Note

For research use only. Not suitable for clinical or therapeutic use.

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