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InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144) (JN987010)

InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144)
InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144)
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  • 100ug
  • 1mg
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Overview
Catalog No.JN987010
Description
InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144) [Iv0144] (JN987010) is a human monoclonal antibody detecting Bifunctional hemolysin/adenylate cyclase in ELISA.
Species reactivityBordetella pertussis
ApplicationsELISA
Host speciesHuman
IsotypeIgG1
Clone IDIv0144
Clonality Monoclonal
Target Bifunctional hemolysin/adenylate cyclase, AC-HLY, ACT, Cyclolysin, Calmodulin-sensitive adenylate cyclase, 4.6.1.1, ATP pyrophosphate-lyase, Adenylyl cyclase, Hemolysin, cya, cyaA, BP0760
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Associated products pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Accession P0DKX7
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Bifunctional hemolysin/adenylate cyclase (cyaA/Cyclolysin) is a ~177 kDa protein. Bifunctional adenylate cyclase toxin-hemolysin that plays a crucial role in host colonization. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function.

1. Glaser, P. et al. (1991) The EMBO journal 10, 1683-8. PMID: 2050107
2. Glaser, P. et al. (1989) The EMBO journal 8, 967-72. PMID: 2542030
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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