InVivoMAb Anti-Human TLR3 Antibody (Iv0178) (HT477010)

Name: InVivoMAb Anti-Human TLR3 Antibody (Iv0178)
Brand: abinScience
SKU: HT477010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Overview

Catalog No.	HT477010
Description	InVivoMAb Anti-Human CD283/TLR3 Antibody (Iv0178) [Iv0178] (HT477010) is a mouse monoclonal antibody detecting TLR3 in Neutralization. Suitable for Human.
Species reactivity	Human
Applications	Neutralization
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG2a, kappa
Clone ID	Iv0178
Target	TLR3, CD283, Toll-like receptor 3
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Associated products	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Accession	O15455
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Toll-like receptor 3 (CD283/TLR3) is a ~103 kDa protein. Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)