InVivoMAb Anti-LASV GPC Antibody (LAVA01) (VK453010)

Name: InVivoMAb Anti-LASV GPC Antibody (LAVA01)
Brand: abinScience
SKU: VK453010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Overview

Catalog No.	VK453010
Description	InVivoMAb Anti-LASV GPC Antibody (LAVA01) [LAVA01] (VK453010) is a human monoclonal antibody detecting Pre-glycoprotein polyprotein GP complex in ELISA, Neutralization.
Species reactivity	Lassa virus (LASV)
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1, kappa
Clone ID	LAVA01
Clonality	Monoclonal
Target	Pre-glycoprotein polyprotein GP complex, Pre-GP-C, Stable signal peptide, SSP, Glycoprotein G1, GP1, Glycoprotein G2, GP2, GPC, GP-C
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Associated products	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Accession	P08669
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Pre-glycoprotein polyprotein GP complex (GPC) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion. 1. Katz, M. et al. (2022) Nature 603, 174-179. PMID: 35173332 2. Eichler, R. et al. (2003) EMBO reports 4, 1084-8. PMID: 14555961
Note	For research use only. Not suitable for clinical or therapeutic use.