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InVivoMAb Anti-Mouse CTLA-4 Antibody (9H10) (MB651020)

InVivoMAb Anti-Mouse CTLA-4 Antibody (9H10)
InVivoMAb Anti-Mouse CTLA-4 Antibody (9H10)
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Spec:
  • 100ug
  • 1mg
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Overview
Catalog No.MB651020
Description
InVivoMAb Anti-Mouse CD152/CTLA4 Antibody (9H10) [9H10] (MB651020) is a mouse monoclonal antibody detecting Cytotoxic T-lymphocyte protein 4 in ELISA, Neutralization. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, Neutralization
Host speciesMouse
IsotypeIgG2a, kappa
Clone ID9H10
Clonality Monoclonal
Target Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, Ctla4, Cd152
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P09793
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-Mouse CTLA-4 Antibody (9H10)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Mouse CD152/CTLA4 Antibody (9H10)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
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