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InVivoMAb Anti-Mouse CD8 alpha Antibody (Iv0165) (MF815010)

InVivoMAb Anti-Mouse CD8 alpha Antibody (Iv0165)
InVivoMAb Anti-Mouse CD8 alpha Antibody (Iv0165)
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  • 1mg
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Overview
Catalog No.MF815010
Description
InVivoMAb Anti-Mouse CD8a/Lyt2 Antibody (Iv0165) [Iv0165] (MF815010) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD8 alpha chain in Neutralization. Suitable for Mouse.
Species reactivityMouse
ApplicationsNeutralization
Host speciesRat
IsotypeIgG2a, kappa
Clone IDIv0165
Clonality Monoclonal
Target T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P01731
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-Mouse CD8 alpha Antibody (Iv0165)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Mouse CD8a/Lyt2 Antibody (Iv0165).

References
Formula
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