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InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018) (VK805020)

InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)
InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)
InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)
InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)
InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)
InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)
Price(USD): $
Spec:
  • 100ug
  • 1mg
Number:
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  • Overview

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  • References

  • Datasheet

Overview
Catalog No.VK805020
Description
InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018) [CR3018] (VK805020) is a human monoclonal antibody detecting Nucleoprotein in ELISA, FCM, IF, Neutralization.
Highlights
  • Multi-Application — Validated across multiple applications.
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivitySevere acute respiratory syndrome coronavirus (SARS-CoV)
ApplicationsELISA, FCM, IF, Neutralization
Host speciesHuman
IsotypeIgG1, kappa
Clone IDCR3018
Clonality Monoclonal
Target Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N Protein, SARS-CoV
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P59595
RRID InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018) (abinScience Cat# VK805020, RRID:AB_3729561)
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Nucleoprotein (NP) is a ~46 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May modulate transforming growth factor-beta signaling by binding host SMAD3.

1. Stertz, S. et al. (2007) Virology 361, 304-15. PMID: 17210170
2. Zhao, X. et al. (2008) The Journal of biological chemistry 283, 3272-3280. PMID: 18055455
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)

  • InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)

    Bioactivity

    Detects recombinant SARS-CoV N protein (Catalog No: VK805052) in indirect ELISA

  • InVivoMAb Anti-SARS-CoV NP/Nucleoprotein Antibody (CR3018)

    Western blot

    Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
    Lane 1: ATG2921 200ng
    Lane 2: 1* loading buffer

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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