Bovine BMP4 Recombinant Protein (N-FC) (BY569011)

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Overview

Catalog No.	BY569011
Description	Recombinant Bovine BMP4 Protein, N-FC (BY569011) expressed in Mammalian Cells, spanning Ser294-Arg409. Purity: >90% by SDS-PAGE. Highlights ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian Cells
Accession	Q2KJH1
Protein length	Ser294-Arg409
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Bos taurus (Bovine)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BMP-2B, BMP-4, BMP2B, BMP4, Bone morphogenetic protein 2B, Bone morphogenetic protein 4, DVR4
Background	Bone morphogenetic protein 4 is a ~46 kDa protein. Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.
Note	For research use only

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Datasheet

Bovine BMP4 Recombinant Protein (N-FC).pdf

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Bovine BMP4 Recombinant Protein (N-FC) (BY569011)

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