Feline IL-31RA Recombinant Protein (C-His) (FV121021)

Name: Feline IL-31RA Recombinant Protein (C-His)
Brand: abinScience
SKU: FV121021
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	FV121021
Description	Recombinant Cat IL31RA Protein, C-His (FV121021) expressed in Mammalian Cells, spanning Val20-Ser516. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	XP_019689862
Protein length	Val20-Ser516
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Felis catus (Cat) (Felis silvestris catus)
Nature	Recombinant
Endotoxin level	<0.1 EU/ug as determined by LAL method.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	59.57 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CRL3, Cytokine receptor-like 3, GLM-R, GPL, Gp130-like monocyte receptor, Gp130-like receptor, IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, IL31RA, Interleukin-31 receptor subunit alpha, ZcytoR17, hGLM-R
Background	Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. 1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449 2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285 3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700 4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637 5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
Note	For research use only

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Datasheet

Feline IL-31RA Recombinant Protein (C-His).pdf

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Formula

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Feline IL-31RA Recombinant Protein (C-His) (FV121021)

Overview

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References

Datasheet

SDS