Canine IL5 Recombinant Protein (C-Strep) (CY218021)

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Overview

Catalog No.	CY218021
Description	Recombinant Dog IL5 Protein, C-Strep (CY218021) expressed in Mammalian Cells, spanning Val22-Ser134. Purity: >90% by SDS-PAGE. Highlights ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian Cells
Accession	Q95J76
Protein length	Val22-Ser134
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Canis lupus familiaris (Dog)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	16.22 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	B-cell differentiation factor I, Eosinophil differentiation factor, IL-5, IL5, Interleukin-5, T-cell replacing factor, TRF
Background	Interleukin-5 is a ~15 kDa protein. Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
Note	For research use only

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Datasheet

Canine IL5 Recombinant Protein (C-Strep).pdf

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Formula

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C₁ × V₁ = C₂ × V₂

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Canine IL5 Recombinant Protein (C-Strep) (CY218021)

Overview

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References

Datasheet

SDS

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