Human ABCC10 Recombinant Protein (N-His) (HB315012)

Name: Human ABCC10 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB315012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HB315012
Description	Recombinant Human ABCC10 Protein, N-His (HB315012) expressed in E. coli, spanning Leu1225-Pro1492. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q5T3U5
Protein length	Leu1225-Pro1492
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	31.19 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ATP-binding cassette sub-family C member 10; 7.6.2.2; 7.6.2.3; Multidrug resistance-associated protein 7; ABCC10; MRP7; SIMRP7
Background	ATP-binding cassette sub-family C member 10 is a ~161 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). May regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Mediates intercellular propagation of antiviral immune signaling in early stages of infection. In RNA virus-infected cells, oligoadenylate synthase senses viral dsRNA and generates 2',5'-oligoadenylates (2-5A) which act as second messengers to activate RNASEL and type I interferon signaling to inhibit viral replication. 1. Chen, ZS. et al. (2003) Molecular pharmacology 63, 351-8. PMID: 12527806 2. Hopper-Borge, E. et al. (2004) Cancer research 64, 4927-30. PMID: 15256465 3. Malofeeva, EV. et al. (2012) Cancer research 72, 6457-67. PMID: 23087055
Note	For research use only

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SDS-PAGE for Recombinant Human ABCC10 Protein, N-His

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Datasheet

Human ABCC10 Recombinant Protein (N-His).pdf

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Human ABCC10 Recombinant Protein (N-His) (HB315012)

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