Human ABCG5 Recombinant Protein (N-His) (HD924012)

Name: Human ABCG5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD924012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD924012
Description	Recombinant Human ABCG5 Protein, N-His (HD924012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9H222
Protein length	His36-Lys349
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ABCG5, ATP-binding cassette sub-family G member 5, EC:7.6.2.-, Sterolin-1
Background	ATP-binding cassette sub-family G member 5 is a ~72 kDa protein. ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity. 1. Lee, JY. et al. (2016) Nature 533, 561-4. PMID: 27144356 2. Berge, KE. et al. (2000) Science (New York, N.Y.) 290, 1771-5. PMID: 11099417 3. Lee, MH. et al. (2001) Nature genetics 27, 79-83. PMID: 11138003 4. Graf, GA. et al. (2004) The Journal of biological chemistry 279, 24881-8. PMID: 15054092 5. Wang, Z. et al. (2006) Biochemistry 45, 9929-39. PMID: 16893193 6. Johnson, BJ. et al. (2010) Biochemistry 49, 3403-11. PMID: 20210363
Note	For research use only

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Datasheet

Human ABCG5 Recombinant Protein (N-His).pdf

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Human ABCG5 Recombinant Protein (N-His) (HD924012)

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