Human ABR Recombinant Protein (N-His) (HD182012)

Name: Human ABR Recombinant Protein (N-His)
Brand: abinScience
SKU: HD182012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD182012
Description	Recombinant Human ABR Protein, N-His (HD182012) expressed in E. coli, spanning Ile285-Ser628. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q12979
Protein length	Ile285-Ser628
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	41.98 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ABR, Active breakpoint cluster region-related protein
Background	Active breakpoint cluster region-related protein is a ~97 kDa protein. Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as a guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form. 1. Cho, YJ. et al. (2007) Molecular and cellular biology 27, 899-911. PMID: 17116687 2. Chuang, TH. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 10282-6. PMID: 7479768
Note	For research use only

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Human ABR Recombinant Protein (N-His).pdf

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Human ABR Recombinant Protein (N-His) (HD182012)

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