

| Catalog No. | HV011022 |
|---|---|
| Description |
Recombinant Human AGXT2 Protein, N-His (HV011022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | Q9BYV1 |
| Protein length | His89-Lys514 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | (R)-3-amino-2-methylpropionate--pyruvate transaminase, AGT 2, AGT2, AGXT2, Alanine--glyoxylate aminotransferase 2, mitochondrial, Beta-ALAAT II, Beta-alanine-pyruvate aminotransferase, D-3-aminoisobutyrate-pyruvate aminotransferase, D-AIBAT, D-beta-aminoisobutyrate-pyruvate aminotransferase, EC:2.6.1.18, EC:2.6.1.40, EC:2.6.1.44 |
| Background | Alanine--glyoxylate aminotransferase 2, mitochondrial is a ~57 kDa protein. Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). 1. Rodionov, RN. et al. (2010) The Journal of biological chemistry 285, 5385-91. PMID: 20018850 2. Caplin, B. et al. (2012) Arteriosclerosis, thrombosis, and vascular biology 32, 2892-900. PMID: 23023372 3. Kittel, A. et al. (2014) PloS one 9, e88544. PMID: 24586340 |
| Note | For research use only |
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