Human AK4/AK3L1 Recombinant Protein (N-His) (HC918012)

Name: Human AK4/AK3L1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC918012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC918012
Description	Recombinant Human AK4/AK3L1 Protein, N-His (HC918012) expressed in E. coli, spanning Met1-Tyr223. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P27144
Protein length	Met1-Tyr223
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	27.43 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	AK3, AK3L1, AK4, Adenylate kinase 3-like, Adenylate kinase 4, mitochondrial, EC:2.7.4.4, EC:2.7.4.6, GTP:AMP phosphotransferase AK4
Background	Adenylate kinase 4, mitochondrial is a ~25 kDa protein. Broad-specificity mitochondrial nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. Phosphorylates only AMP when using GTP as phosphate donor. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. 1. Liu, R. et al. (2009) Biochemical and biophysical research communications 379, 92-7. PMID: 19073142 2. Panayiotou, C. et al. (2010) The international journal of biochemistry & cell biology 42, 62-9. PMID: 19766732 3. Amiri, M. et al. (2013) The international journal of biochemistry & cell biology 45, 925-31. PMID: 23416111 4. Lanning, NJ. et al. (2014) Cell reports 7, 907-17. PMID: 24767988
Note	For research use only

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Datasheet

Human AK4/AK3L1 Recombinant Protein (N-His).pdf

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Human AK4/AK3L1 Recombinant Protein (N-His) (HC918012)

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