Human ARHGEF5 Recombinant Protein (N-His) (HC702012)

Name: Human ARHGEF5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC702012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC702012
Description	Recombinant Human ARHGEF5 Protein, N-His (HC702012) expressed in E. coli, spanning Ser1136-Ala1597. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q12774
Protein length	Ser1136-Ala1597
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	55.93 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ARHGEF5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Rho guanine nucleotide exchange factor 5, TIM, Transforming immortalized mammary oncogene, p60 TIM
Background	Rho guanine nucleotide exchange factor 5 is a ~176 kDa protein. Guanine nucleotide exchange factor which activates Rho GTPases. Strongly activates RHOA. Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1. Involved in regulation of cell shape and actin cytoskeletal organization. Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia. 1. Xie, X. et al. (2005) Cellular signalling 17, 461-71. PMID: 15601624 2. Debily, MA. et al. (2004) Human molecular genetics 13, 323-34. PMID: 14662653
Note	For research use only

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Datasheet

Human ARHGEF5 Recombinant Protein (N-His).pdf

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Human ARHGEF5 Recombinant Protein (N-His) (HC702012)

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