

| Catalog No. | HS942012 |
|---|---|
| Description |
Recombinant Human ARL13B Protein, N-His (HS942012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | Q3SXY8 |
| Protein length | Met1-Thr243 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1, ARL13B, ARL2-like protein 1, ARL2L1 |
| Background | ADP-ribosylation factor-like protein 13B is a ~48 kDa protein. Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze fit; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. 1. Lin, Z. et al. (2024) Journal of cellular physiology 239, e31189. PMID: 38219074 2. Barral, DC. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 21354-9. PMID: 23223633 |
| Note | For research use only |
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