Human ARPP19 Recombinant Protein (N-GST & C-His) (HX213022)

Name: Human ARPP19 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HX213022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HX213022
Description	Recombinant Human ARPP19 Protein, N-GST & C-His (HX213022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P56211
Protein length	Ser2-Leu77
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ARPP-19, ARPP19, cAMP-regulated phosphoprotein 19
Background	cAMP-regulated phosphoprotein 19 is a ~12 kDa protein. Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Inhibition of PP2A is enhanced when ARPP19 is phosphorylated. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression. 1. Padi, SKR. et al. (2024) Nature 625, 195-203. PMID: 38123684 2. Gharbi-Ayachi, A. et al. (2010) Science (New York, N.Y.) 330, 1673-7. PMID: 21164014
Note	For research use only

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Datasheet

Human ARPP19 Recombinant Protein (N-GST & C-His).pdf

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Human ARPP19 Recombinant Protein (N-GST & C-His) (HX213022)

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Datasheet

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