Human AVPR2 Recombinant Protein (N-His-KSI) (HD776012)

Name: Human AVPR2 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD776012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD776012
Description	Recombinant Human AVPR2 Protein, N-His-KSI (HD776012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P30518
Protein length	Leu2-Ser371
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ADHR, AVPR V2, AVPR2, Antidiuretic hormone receptor, DIR, DIR3, Renal-type arginine vasopressin receptor, V2R, Vasopressin V2 receptor
Background	Vasopressin V2 receptor is a ~40 kDa protein. G-protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). AVPR2 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. 1. Birnbaumer, M. et al. (1992) Nature 357, 333-5. PMID: 1534149 2. Böselt, I. et al. (2009) PloS one 4, e5573. PMID: 19440390 3. Wang, L. et al. (2021) Cell research 31, 932-934. PMID: 33664408 4. Zhou, F. et al. (2021) Cell research 31, 929-931. PMID: 33742150
Note	For research use only

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Datasheet

Human AVPR2 Recombinant Protein (N-His-KSI).pdf

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Human AVPR2 Recombinant Protein (N-His-KSI) (HD776012)

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