

| Catalog No. | HD881012 |
|---|---|
| Description |
Recombinant Human AWAT2 Protein, N-His (HD881012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | Q6E213 |
| Protein length | Gly66-Ile333 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | 11-cis-RE-synthase, 11-cis-specific retinyl-ester synthase, ARAT, AWAT2, Acyl-CoA retinol O-fatty-acyltransferase, Acyl-CoA wax alcohol acyltransferase 2, DC4, DGAT2L4, Diacylglycerol O-acyltransferase 2-like protein 4, Diacylglycerol O-acyltransferase candidate 4, EC:2.3.1.20, EC:2.3.1.75, EC:2.3.1.76, Long-chain-alcohol O-fatty-acyltransferase 2, MFAT, Multifunctional O-acyltransferase, Retinol O-fatty-acyltransferase, WS, Wax synthase, hDC4, hWS |
| Background | Acyl-CoA wax alcohol acyltransferase 2 is a ~38 kDa protein. Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters. Shows a preference for medium chain acyl-CoAs from C12 to C16 in length and fatty alcohols shorter than C20, as the acyl donors and acceptors, respectively. Also possesses acyl-CoA retinol acyltransferase (ARAT) activity that preferentially esterifies 11-cis-retinol, a chromophore precursor of bleached opsin pigments in cone cells. Shows higher catalytic efficiency toward 11-cis-retinol versus 9-cis-retinol, 13-cis-retinol, and all-trans-retinol substrates. 1. Cheng, JB. et al. (2004) The Journal of biological chemistry 279, 37798-807. PMID: 15220349 2. Turkish, AR. et al. (2005) The Journal of biological chemistry 280, 14755-64. PMID: 15671038 3. Yen, CL. et al. (2005) Journal of lipid research 46, 2388-97. PMID: 16106050 4. Ma, Z. et al. (2017) Journal of lipid research 58, 1091-1099. PMID: 28420705 5. Kaylor, JJ. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 7302-7. PMID: 24799687 |
| Note | For research use only |
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