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Human BCAP31 Recombinant Protein (N-His) (HD941012)

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Overview
Catalog No.HD941012
Description
Recombinant Human BCAP31 Protein, N-His (HD941012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
Expression systemE. coli
AccessionP51572
Protein lengthLeu168-Leu233
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BAP31, BCAP31, BCR-associated protein 31, Bap31, DXS1357E, Protein CDM, p28
Background

B-cell receptor-associated protein 31 is a ~27 kDa protein. Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40.

1. Wakana, Y. et al. (2008) Molecular biology of the cell 19, 1825-36. PMID: 18287538
2. Annaert, WG. et al. (1997) The Journal of cell biology 139, 1397-410. PMID: 9396746
3. Namba, T. (2019) Science advances 5, eaaw1386. PMID: 31206022
4. Nguyen, M. et al. (2000) Molecular and cellular biology 20, 6731-40. PMID: 10958671
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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