Human CARD16 Recombinant Protein (N-His) (HD285012)

Name: Human CARD16 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD285012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD285012
Description	Recombinant Human CARD16 Protein, N-His (HD285012) expressed in E. coli, spanning Met1-Ser197. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q5EG05
Protein length	Met1-Ser197
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	24.79 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CARD-only protein 1, CARD16, COP, COP1, Caspase recruitment domain-containing protein 16, Caspase recruitment domain-only protein 1, Caspase-1 inhibitor COP, Pseudo interleukin-1 beta converting enzyme, Pseudo-ICE, Pseudo-IL1B-converting enzyme
Background	Caspase recruitment domain-containing protein 16 is a ~22 kDa protein. Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death.
Note	For research use only

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Datasheet

Human CARD16 Recombinant Protein (N-His).pdf

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Human CARD16 Recombinant Protein (N-His) (HD285012)

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