Human CBFA2T2 Recombinant Protein (N-His) (HD777012)

Name: Human CBFA2T2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD777012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD777012
Description	Recombinant Human CBFA2T2 Protein, N-His (HD777012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	O43439
Protein length	Ala109-Asn213
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CBFA2T2, EHT, ETO homologous on chromosome 20, MTG8-like protein, MTG8-related protein 1, MTGR1, Myeloid translocation-related protein 1, Protein CBFA2T2, p85
Background	Protein CBFA2T2 is a ~67 kDa protein. Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Via association with PRDM14 is involved in regulation of embryonic stem cell (ESC) pluripotency. Involved in primordial germ cell (PCG) formation. Stabilizes PRDM14 and OCT4 on chromatin in a homooligomerization-dependent manner. Can repress the expression of MMP7 in a ZBTB33-dependent manner. 1. Davis, JN. et al. (2003) Gene 303, 1-10. PMID: 12559562 2. Rossetti, S. et al. (2004) Genomics 84, 1-9. PMID: 15203199 3. Tu, S. et al. (2016) Nature 534, 387-90. PMID: 27281218 4. Barrett, CW. et al. (2012) PloS one 7, e51205. PMID: 23251453
Note	For research use only

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Datasheet

Human CBFA2T2 Recombinant Protein (N-His).pdf

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Human CBFA2T2 Recombinant Protein (N-His) (HD777012)

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