Human CBLL1 Recombinant Protein (N-GST & C-His) (HP915022)

Name: Human CBLL1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HP915022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP915022
Description	Recombinant Human CBLL1 Protein, N-GST & C-His (HP915022) expressed in E. coli, spanning Lys117-His190. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q75N03
Protein length	Lys117-His190
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	36.77 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CBLL1, Casitas B-lineage lymphoma-transforming sequence-like protein 1, E3 ubiquitin-protein ligase Hakai, EC:2.3.2.27, HAKAI, RING finger protein 188, RING-type E3 ubiquitin transferase Hakai, RNF188, c-Cbl-like protein 1
Background	E3 ubiquitin-protein ligase Hakai is a ~54 kDa protein. E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown. 1. Yue, Y. et al. (2018) Cell discovery 4, 10. PMID: 29507755
Note	For research use only

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Datasheet

Human CBLL1 Recombinant Protein (N-GST & C-His).pdf

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Human CBLL1 Recombinant Protein (N-GST & C-His) (HP915022)

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