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Human CD120b/TNFRSF1B/TNFR2 Recombinant Protein (C-Fc) (HB070021)

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Human CD120b/TNFRSF1B/TNFR2 Recombinant Protein (C-Fc)

Human CD120b/TNFRSF1B/TNFR2 Recombinant Protein (C-Fc)

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Datasheet
SDS

Overview

Catalog No.	HB070021
Description	Recombinant Human CD120b/TNFRSF1B/TNFR2 Protein, C-Fc (HB070021) expressed in Mammalian Cells, spanning Met1-Asp257. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian Cells
Accession	P20333
Protein length	Met1-Asp257
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD120b, Etanercept, TBP-2, TBPII, TNF-R2, TNF-RII, TNFBR, TNFR-II, TNFR2, TNFRSF1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor superfamily member 1b, membrane form, Tumor necrosis factor receptor type II, Tumor necrosis factor-binding protein 2, p75, p80 TNF-alpha receptor
Background	Tumor necrosis factor receptor superfamily member 1B is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity.
Note	For research use only

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SDS-PAGE

SDS-PAGE for Recombinant Human CD120b/TNFRSF1B/TNFR2 Protein, C-Fc

References

Datasheet

Human CD120b/TNFRSF1B/TNFR2 Recombinant Protein (C-Fc).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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Human CD120b/TNFRSF1B/TNFR2 Recombinant Protein (C-Fc)