Human CD167b/DDR2 Recombinant Protein (C-Fc) (HS877031)

Name: Human CD167b/DDR2 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HS877031
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	HS877031
Description	Recombinant Human CD167b/DDR2 Protein, C-Fc (HS877031) expressed in Mammalian Cells, spanning Met1-Arg399. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q16832
Protein length	Met1-Arg399
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	71.46 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD167 antigen-like family member B, CD167b, DDR2, Discoidin domain receptor 2, Discoidin domain-containing receptor 2, Discoidin domain-containing receptor tyrosine kinase 2, EC:2.7.10.1, NTRKR3, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, TKT, TYRO10, Tyrosine-protein kinase TYRO10
Background	Discoidin domain-containing receptor 2 is a ~96 kDa protein. Tyrosine kinase involved in the regulation of tissues remodeling. It functions as a cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. 1. Xu, L. et al. (2018) American journal of human genetics 103, 976-983. PMID: 30449416
Note	For research use only

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Datasheet

Human CD167b/DDR2 Recombinant Protein (C-Fc).pdf

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Human CD167b/DDR2 Recombinant Protein (C-Fc) (HS877031)

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