Human CHMP1A Recombinant Protein (N-His) (HD962012)

Name: Human CHMP1A Recombinant Protein (N-His)
Brand: abinScience
SKU: HD962012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD962012
Description	Recombinant Human CHMP1A Protein, N-His (HD962012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9HD42
Protein length	Met1-Asn196
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CHMP1, CHMP1A, CHMP1a, Charged multivesicular body protein 1a, Chromatin-modifying protein 1a, KIAA0047, PCOLN3, PRSM1, Vacuolar protein sorting-associated protein 46-1, Vps46-1, hVps46-1
Background	Charged multivesicular body protein 1a is a ~21 kDa protein. Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
Note	For research use only

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Datasheet

Human CHMP1A Recombinant Protein (N-His).pdf

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Human CHMP1A Recombinant Protein (N-His) (HD962012)

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