Human CLCN4 Recombinant Protein (N-His) (HW578012)

Name: Human CLCN4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HW578012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HW578012
Description	Recombinant Human CLCN4 Protein, N-His (HW578012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P51793
Protein length	Arg593-Asn760
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CLCN4, Chloride channel protein 4, Chloride transporter ClC-4, ClC-4, H(+)/Cl(-) exchange transporter 4
Background	H(+)/Cl(-) exchange transporter 4 is a ~84 kDa protein. Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. 1. Zdebik, AA. et al. (2008) The Journal of biological chemistry 283, 4219-27. PMID: 18063579 2. Veeramah, KR. et al. (2013) Epilepsia 54, 1270-81. PMID: 23647072 3. Hu, H. et al. (2016) Molecular psychiatry 21, 133-48. PMID: 25644381 4. Palmer, EE. et al. (2018) Molecular psychiatry 23, 222-230. PMID: 27550844 5. Guzman, RE. et al. (2017) The Journal of biological chemistry 292, 19055-19065. PMID: 28972156 6. Jentsch, TJ. et al. (2018) Physiological reviews 98, 1493-1590. PMID: 29845874
Note	For research use only

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Datasheet

Human CLCN4 Recombinant Protein (N-His).pdf

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Human CLCN4 Recombinant Protein (N-His) (HW578012)

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