Human CLIC5 Recombinant Protein (N-His) (HD391012)

Name: Human CLIC5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD391012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD391012
Description	Recombinant Human CLIC5 Protein, N-His (HD391012) expressed in E. coli, spanning Pro173-Ser410. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q9NZA1
Protein length	Pro173-Ser410
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	29.16 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CLIC5, Chloride intracellular channel protein 5, EC:1.8.-.-, Glutaredoxin-like oxidoreductase CLIC5
Background	Chloride intracellular channel protein 5 is a ~46 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Can insert into membranes and form non-selective ion channels almost equally permeable to Na(+), K(+) and Cl(-). Required for normal hearing. It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti. May play a role in the regulation of transepithelial ion absorption and secretion. 1. Berryman, M. et al. (2004) The Journal of biological chemistry 279, 34794-801. PMID: 15184393 2. Singh, H. et al. (2007) The FEBS journal 274, 6306-16. PMID: 18028448 3. Seco, CZ. et al. (2015) European journal of human genetics : EJHG 23, 189-94. PMID: 24781754 4. Wegner, B. et al. (2010) American journal of physiology. Renal physiology 298, F1492-503. PMID: 20335315
Note	For research use only

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Datasheet

Human CLIC5 Recombinant Protein (N-His).pdf

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Human CLIC5 Recombinant Protein (N-His) (HD391012)

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