Human CLK1 Recombinant Protein (N-His) (HD047012)

Name: Human CLK1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD047012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD047012
Description	Recombinant Human CLK1 Protein, N-His (HD047012) expressed in E. coli, spanning Ser153-Ile484. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P49759
Protein length	Ser153-Ile484
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	41.08 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CDC-like kinase 1, CLK, CLK1, Dual specificity protein kinase CLK1, EC:2.7.12.1
Background	Dual specificity protein kinase CLK1 is a ~57 kDa protein. Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. 1. Moeslein, FM. et al. (1999) The Journal of biological chemistry 274, 26697-704. PMID: 10480872 2. Eisenreich, A. et al. (2009) Circulation research 104, 589-99. PMID: 19168442
Note	For research use only

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Datasheet

Human CLK1 Recombinant Protein (N-His).pdf

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Human CLK1 Recombinant Protein (N-His) (HD047012)

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