Human CREB3 Recombinant Protein (N-His) (HD964012)

Name: Human CREB3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD964012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD964012
Description	Recombinant Human CREB3 Protein, N-His (HD964012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	O43889
Protein length	Lys145-Thr251
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CREB-3, CREB3, Cyclic AMP-responsive element-binding protein 3, LZIP, Leucine zipper protein, Luman, N-terminal Luman, Processed cyclic AMP-responsive element-binding protein 3, Transcription factor LZIP-alpha, Transcriptionally active form, cAMP-responsive element-binding protein 3
Background	Cyclic AMP-responsive element-binding protein 3 is a ~41 kDa protein. Endoplasmic reticulum (ER)-bound sequence-specific transcription factor that directly binds DNA and activates transcription. Plays a role in the unfolded protein response (UPR), promoting cell survival versus ER stress-induced apoptotic cell death. Also involved in cell proliferation, migration and differentiation, tumor suppression and inflammatory gene expression. Acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Associates with chromatin to the HERPUD1 promoter. 1. Luciano, RL. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 10757-62. PMID: 10984507 2. DenBoer, LM. et al. (2005) Biochemical and biophysical research communications 331, 113-9. PMID: 15845366 3. Liang, G. et al. (2006) Molecular and cellular biology 26, 7999-8010. PMID: 16940180 4. Kang, H. et al. (2009) Molecular endocrinology (Baltimore, Md.) 23, 1746-57. PMID: 19779205 5. Lu, R. et al. (1997) Molecular and cellular biology 17, 5117-26. PMID: 9271389 6. Ko, J. et al. (2004) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18, 890-2. PMID: 15001559 7. Jang, SW. et al. (2007) The Journal of biological chemistry 282, 11092-100. PMID: 17296613
Note	For research use only

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Datasheet

Human CREB3 Recombinant Protein (N-His).pdf

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Human CREB3 Recombinant Protein (N-His) (HD964012)

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