Human ELK4 Recombinant Protein (N-His) (HC919012)

Name: Human ELK4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC919012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC919012
Description	Recombinant Human ELK4 Protein, N-His (HC919012) expressed in E. coli, spanning Met1-Gly132. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P28324
Protein length	Met1-Gly132
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	17.44 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ELK4, ETS domain-containing protein Elk-4, SAP-1, SAP1, SRF accessory protein 1, Serum response factor accessory protein 1
Background	ETS domain-containing protein Elk-4 is a ~46 kDa protein. Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.
Note	For research use only

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Datasheet

Human ELK4 Recombinant Protein (N-His).pdf

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Human ELK4 Recombinant Protein (N-His) (HC919012)

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